PDRN Injection in Malaysia (2026): Benefits, Sessions, Safety & Who It's For

PDRN injections — often called “salmon DNA” or “salmon sperm” injections — have become one of the most searched skin treatments in Malaysia. Unlike fillers, PDRN doesn't add volume. It works as a skin-repair booster, helping damaged, thin or dull skin heal and regenerate. Here's what it does, who it suits, and what to look for in a clinic.

What Is PDRN?

PDRN (polydeoxyribonucleotide) is a purified DNA fragment, usually derived from salmon, that is highly compatible with human tissue. Originally used in medicine for wound healing, it supports cell repair, improves micro-circulation and calms inflammation. In aesthetics, it's injected into the skin in tiny amounts to improve skin quality from within. Read more on our PDRN injection treatment page.

What Can PDRN Help With?

• Dull, tired or uneven skin tone

• Fine lines and thin, crepey skin

• Enlarged pores and rough texture

• Shallow acne scars and post-acne redness (often combined with laser)

• Sensitised or damaged skin barrier, and faster recovery after laser

• Delicate under-eye skin

PDRN vs Other Skin Boosters

Hyaluronic acid boosters focus mainly on hydration and glow, while PDRN focuses on repair and regeneration. Many patients benefit from combining both. If you're deciding between options, read our comparison of Profhilo vs Skinvive vs PDRN, or explore our skin booster treatments and K-Booster.

How Many Sessions Do You Need?

A typical course is about 3 sessions spaced 2–4 weeks apart, followed by maintenance every few months. Skin often looks fresher within 1–2 weeks of the first session, with texture and firmness continuing to improve over the course. For acne scars, PDRN is usually one part of a plan that may include acne scar treatments such as laser or SkinPen microneedling.

Procedure and Downtime

After numbing cream, PDRN is placed with fine micro-injections across the face (or with a device-assisted technique). The appointment takes around 30–45 minutes. Small bumps settle within a day, and pinpoint bruising can occur. Most people return to normal activities the same or next day; avoid makeup for about 12–24 hours.

Why Product Quality and the Injector Matter

PDRN's popularity has brought many products and providers into the market, and quality varies widely. At Dr Jane Clinic, PDRN is administered by a doctor using genuine, registered products opened in front of you. Before treatment, the doctor reviews your skin concerns, allergies (including fish allergy) and current skincare, and decides whether PDRN alone or a combination plan will get you the best result. We take before photos and review your skin between sessions, so you can see the progress for yourself. See real results in our before & after gallery and meet the doctor on our About Dr Jane page.

Book Your PDRN Consultation in Petaling Jaya

Want healthier, clearer, more resilient skin? Book your PDRN consultation online or call +6014-937 5263. Dr Jane Clinic, Tropicana Avenue, Petaling Jaya.

Frequently Asked Questions

Is PDRN the same as salmon sperm injection?

Yes, the terms are used interchangeably. PDRN is a highly purified DNA fragment, typically from salmon.

Is PDRN safe?

It is generally well tolerated when a registered product is injected by a doctor. Tell your doctor if you have a fish allergy.

When will I see results?

Many patients notice fresher skin within 1–2 weeks, with the best results after completing a course of about 3 sessions.

This article is general information, not medical advice. Results vary between individuals.